fbpx

IT Blog

Uncategorized

Carle Illinois researchers among Cancer Center at Illinois 2022 grant recipients – Carle Illinois College of Medicine

We Are Physician Innovators
Researchers at Carle Illinois College of Medicine are leading interdisciplinary cancer research projects receiving funding through the Cancer Center at Illinois (CCIL) developmental grant awards. CCIL grants provide support to Illinois scientists to drive cancer research collaborations on the University of Illinois Urbana-Champaign campus and encourage engineering, technology, and science-based researchers to engage with clinical collaborators.
“Cancer Center at Illinois Seed, Planning, Bridge, and other grant awards support novel collaborations that lead to transformative advances in cancer research. Over the past five years, these CCIL funding opportunities have produced new cancer focused research grants, earned significant external funding, and launched translational clinical partnerships that will change the cancer care landscape for years to come,” said Rohit Bhargava, CCIL Director.
Six of the cancer research projects received CCIL Seed Grant awards – designed to enhance team-based science to pursue innovative discovery and translational directions that lead to major external funding opportunities. The Seed Grant recipients include:

Project Title: A Molecular Lego Kit for Kinase Inhibitors
Principal Investigator: Martin Burke, Professor, Chemistry & Carle Illinois College of Medicine
Research Team: Emad Tajkhorshid, Professor, Biochemistry & Carle Illinois College of Medicine
 
 
 
 
Project Title: Engineering Mechanical and Chemical Gradients to Control Cancer Cell Metastasis
Principal Investigator: Catherine Murphy, Professor, Chemistry & Carle Illinois College of Medicine
Research Team: Taher Saif, Professor, Mechanical Sciences and Engineering & Carle Illinois College of Medicine
 
 
Project Title: Versatile Redox Detection of a-Glycosylated Proteins in Blood, A Potential Universal Biomarker for Robust Cancer Detection
Principal Investigator: Joaquín Rodríguez López, Associate Professor, Chemistry
Research Team: Brian Cunningham, Professor, Electrical and Computer Engineering & Carle Illinois College of Medicine; Zeynep Madak-Erdogan, Associate Professor, Food Science and Human Nutrition & Health Innovation Professor at Carle Illinois College of Medicine
 
Project Title: Molecular Dynamics Modeling of Target Recycling Amplification for Ultrasensitive Detection of RNA-based Cancer Biomarkers
Principal Investigator: Emad Tajkhorshid, Professor, Biochemistry & Carle Illinois College of Medicine
Research Team: Brian Cunningham, Professor, Electrical and Computer Engineering & Carle Illinois College of Medicine
 
 
Project Title: Targeting the Bidirectional Crosstalk Between Gut Microbial Metabolism and Bile Acids to Alleviate Intestinal and Liver Tumorigenesis
Principal Investigator: Christopher Gaulke, Assistant Professor, Pathobiology
Research Team: Sayeepriyadarshini Anakk, Associate Professor, Molecular & Integrative Physiology; Collin Kieffer, Assistant Professor, Microbiology; Bo Wang, Assistant Professor, Comparative Biosciences
Project Title: Optogenetic Modulation of the Tumor Microenvironment to Improve Cancer Immunotherapy
Principal Investigator: Kai Zhang, Associate Professor, Biochemistry
Research Team: Erik Nelson, Associate Professor, Molecular and Integrative Physiology
Three of the cancer research projects received CCIL Planning and Bridge Awards. CCIL Planning Grants are one-time awards to individuals or teams to develop research concepts, take advantage of a unique research opportunity, stimulate a high-priority research area, or initiate a potentially impactful, but risky project. CCIL Bridge grants aid cancer-focused research grant proposals at the R01 or multi-project level in overcoming funding barriers. The grant recipients include:
Project Title: Delineating and Targeting Metabolic Adaptations in the Breast Cancer-Metastatic Niche Nexus to Improve Therapy Efficacy
Principal Investigator: Zeynep Madak-Erdogan, Associate Professor, Food Science and Human Nutrition & Health Innovation Professor at the Carle Illinois College of Medicine
 
 
 
 
Project Title: Metabolic Tagging of Tumor Exosomes for Developing Enhanced Exosome Vaccines
Principal Investigator: Hua Wang, Assistant Professor, Materials Science and Engineering & Carle Illinois College of Medicine
Research Team: Erik Nelson, Associate Professor, Molecular and Integrative Physiology
Project Title: Using Enzyme/Small-molecule Pairs to Engineer Selectively in Targeting Cancer
Principal Investigator: Angad Mehta, Assistant Professor, Chemistry 
Research Team: Wenyan Mei, Assistant Professor, Comparative Biosciences
“This cohort of CCIL grant recipients is truly representative of the University’s leadership in engineering, technology, and basic sciences. These multidisciplinary teams are leading innovative discoveries in high-priority research areas with the long-term goal of providing cancer solutions with improved quality and accessibility, lower costs, and personalized to meet the individual needs of cancer patients,” said Paul Hergenrother, CCIL Deputy Director.
Editor’s note: The original version of this article by Jordan Goebig, CCIL Communications Manager, can be found here.
A partnership between the University of Illinois Urbana-Champaign and Carle Health
Carle Illinois College of Medicine
University of Illinois
506 South Mathews Ave
Urbana, IL 61801

medicine@illinois.edu
217-300-5700

Copyright
Privacy Policy
Powered by SiteManager | Contact Webmaster

source